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Ref-1 inhibitor PNRI-299 reduces allergy airway inflammation. (a) OVA-treated mice have a dense inflammatory cell infiltrate (arrows) surrounding the airways (AW) and blood vessels (BV) and mucus hypersecretion not seen in saline controls (c). (b) PNRI-299 (0.75 mg/kg) reduced the airway inflammatory cell infiltration (arrows) and mucus release in OVA-treated mice.
