Table 2. Two-point lod scores at 17p13.3–p11.2.
Position | Lod Score at θ= | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
Marker | Mb | cM a | Zmaxb | θMLE c | 0.00 | 0.05 | 0.10 | 0.20 | 0.30 | 0.40 |
GTAT1A05 | 0.57 | 4.52 | 2.87 | 0.00 | 2.87 | 2.53 | 2.18 | 1.46 | 0.77 | 0.23 |
D17S919 | 3.64 | 13.24 | 0.59 | 0.15 | −∞ | 0.43 | 0.58 | 0.54 | 0.35 | 0.14 |
D17S1828 | 3.76 | 13.74 | 1.28 | 0.10 | −∞ | 1.08 | 1.28 | 1.04 | 0.58 | 0.18 |
D17S559 | 4.69 | (15.5) | 1.86 | 0.00 | 1.86 | 1.71 | 1.53 | 1.14 | 0.71 | 0.28 |
GATA158H04 | 6.27 | 19.97 | 3.65 | 0.00 | 3.65 | 3.23 | 2.81 | 1.97 | 1.14 | 0.42 |
D17S906 | 6.64 | 20.99 | 3.24 | 0.00 | 3.24 | 2.83 | 2.41 | 1.56 | 0.76 | 0.20 |
D17S1353 | 7.56 | 23.31 | 3.90 | 0.00 | 3.90 | 3.42 | 2.93 | 1.94 | 0.99 | 0.26 |
GATA7B03 | 8.14 | (23.4) | 4.57 | 0.00 | 4.57 | 4.05 | 3.51 | 2.42 | 1.34 | 0.42 |
D17S1844 | 8.56 | 24.61 | 3.90 | 0.00 | 3.90 | 3.44 | 2.98 | 2.06 | 1.18 | 0.42 |
D17S1791 | 9.10 | 26.87 | 1.52 | 0.10 | −∞ | 1.32 | 1.52 | 1.28 | 0.77 | 0.25 |
D17S945 | 9.76 | 30.55 | 1.12 | 0.15 | −∞ | 0.82 | 1.10 | 1.03 | 0.66 | 0.22 |
GATA8C04 | 10.46 | 33.56 | 1.01 | 0.15 | −∞ | 0.69 | 0.98 | 0.94 | 0.65 | 0.27 |
ATA78D02 | 13.06 | (40.4) | 0.33 | 0.15 | −2.34 | −0.06 | 0.24 | 0.32 | 0.18 | 0.02 |
GATA185H04 | 17.21 | 50.99 | 0.40 | 0.25 | −∞ | −0.66 | 0.00 | 0.38 | 0.34 | 0.13 |
Estimated cM distances are given in parentheses.
Maximum two-point lod score with Superlink (autosomal recessive, full penetrance).
Maximum likelihood estimate of recombination fraction (θ).