Table 2. APOA5 genotype and haplotype in relation to log-transformed plasma triglycerides.

SNP or haplotype	Frequency of minor	All subjects		Men		Women
	allele or haplotype	Regression coefficient	P-value	Regression coefficient	P-value	Regression coefficient	P-value
Hong Kong
rs662799	0.288	0.067	2.6 × 10−13	0.098	1.3 × 10−12	0.042	0.00031
rs17120035	0.064	−0.024	0.159	−0.042	0.109	−0.004	0.868
rs9804646	0.217	−0.042	5.3 × 10−5	−0.045	0.0042	−0.037	0.0048
rs1729410	0.404	−0.007	0.444	−0.010	0.434	−0.005	0.666
rs633389	0.345	−0.006	0.532	−0.002	0.862	−0.008	0.468
TGGCG	0.322	−0.032	0.00069	−0.052	0.00024	−0.016	0.182
CGGGG	0.152	0.046	0.00020	0.067	0.00053	0.031	0.047
TGAGA	0.150	−0.043	0.00042	−0.035	0.059	−0.048	0.0015
TGGGA	0.108	0.007	0.602	−0.002	0.921	0.014	0.443
CGGCG	0.075	0.087	8.1 × 10−7	0.129	6.4 × 10−7	0.051	0.030
CGGGA	0.059	0.086	2.6 × 10−5	0.116	0.00021	0.062	0.018
TGGGG	0.059	−0.032	0.111	−0.058	0.060	−0.015	0.555
Guangzhou
rs662799	0.293	0.057	1.3 × 10−12	0.067	1.5 × 10−8	0.048	5.6 × 10−6
Hong Kong + Guangzhou*
rs662799	0.291	0.061	9.2 × 10−24	0.080	1.3 × 10−18	0.045	8.9 × 10−9

The haplotypes comprise the SNPs rs662799, rs17120035, rs9804646, rs1729410 and rs633389.

P-values were adjusted by linear regression for age, sex (except in sex-specific group), education (≤primary, secondary and ≥tertiary), current smoking and alcohol drinking.

^*P-values were further adjusted for study site.