Table 3. SimWalk multipoint parametric linkage analysis of the HCHOLA4 locus in 18 families.
| SimWalk multipoint LOD (θ=0) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Nb. | Nb. | ELOD | D16S3031 | D16S3107 | D16S3067 | D16S3106 | D16S3018 | |||
| Familly | Subjects | Affected | meiosis | av. | max. | 64 338 902 | 66 215 433 | 67 666 169 | 70 745 261 | 72 730 203 |
| HC14 | 13 | 10 | 9 | 1.29 | 1.80 | −7.84 | −7.19 | −6.85 | −9.16 | −6.49 |
| HC32 | 4 | 3 | 2 | 0.12 | 0.26 | −0.74 | −0.74 | −0.74 | −0.74 | NA |
| HC35 | 5 | 4 | 3 | 0.45 | 0.60 | −1.85 | −2.39 | −2.26 | −2.71 | NA |
| HC38 | 4 | 3 | 2 | 0.23 | 0.30 | 0.30 | 0.30 | 0.30 | 0.30 | 0.30 |
| HC42 | 6 | 4 | 5 | 0.55 | 0.81 | −2.85 | −2.29 | −2.15 | −2.89 | −2.99 |
| HC49 | 4 | 3 | 2 | 0.23 | 0.30 | 0.30 | 0.30 | 0.30 | 0.30 | 0.30 |
| HC73 | 15 | 4 | 10 | 1.06 | 1.69 | −8.18 | −7.16 | −6.48 | −10.06 | −7.29 |
| HC120 | 4 | 3 | 2 | 0.22 | 0.30 | 0.30 | 0.30 | 0.30 | 0.28 | 0.26 |
| HC122 | 8 | 4 | 5 | 0.70 | 1.12 | −0.19 | −0.14 | −0.12 | −0.10 | −0.04 |
| HC126 | 11 | 3 | 6 | 0.59 | 1.21 | −2.21 | −3.21 | −3.21 | −1.65 | −0.62 |
| HC136 | 5 | 4 | 3 | 0.44 | 0.60 | −2.51 | 0.60 | 0.60 | 0.60 | 0.60 |
| HC138 | 6 | 5 | 4 | 0.53 | 0.9 | −6.57 | −5.14 | −4.95 | −5.36 | −4.87 |
| HC205 | 6 | 3 | 4 | 0.50 | 0.86 | 0.86 | 0.86 | 0.86 | 0.86 | 0.86 |
| HC218 | 4 | 3 | 2 | 0.11 | 0.26 | −0.74 | −0.74 | −0.73 | −0.74 | −0.74 |
| HC257 | 5 | 4 | 3 | 0.44 | 0.60 | −1.75 | −2.14 | −2.13 | −2.67 | −1.24 |
| HC266 | 5 | 3 | 3 | 0.33 | 0.56 | 0.56 | 0.56 | 0.56 | 0.56 | 0.56 |
| HC374 | 8 | 5 | 4 | 0.68 | 0.9 | −1.85 | −1.80 | −1.84 | −2.41 | −2.55 |
| HC438 | 10 | 6 | 6 | 1.18 | 2.52 | −4.88 | −3.57 | −3.26 | −3.18 | −8.59 |