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. 2003 Jan 16;100(3):1209–1214. doi: 10.1073/pnas.0237043100

Figure 2.

Figure 2

VH-to-DJH rearrangement is reduced in developing B cells from core RAG2 mice. (A) PCR analysis of DH-to-JH rearrangement in fetal liver genomic DNA from RAG WT (+/c) and core (c/c) littermates is shown with serial dilutions from 14.5-dpc embryos (Right). (Left) PCR amplification of Cμ is included as a loading control and shown at the bottom. (B) PCR analysis of VH-to-DJH rearrangement of VH7183 and VHQ52 segments with serial dilutions for VH7183 rearrangements from 15.5-dpc embryos (Right). PCR products were probed with the JH4 probe.