Table 6.
Median (10th, 90th centiles) for 2 matrix metalloproteins (MMP-1 and MMP-9) on 3 different days presented separately for 3 gestational age categories in the entire sample and then in samples stratified by whether or not the placenta was inflamed. Protein concentrations are pg/mg total protein
Protein | Median (10th, 90th centile) | |||
---|---|---|---|---|
GA | Day 1 | Day 7 | Day 14 | |
Entire sample | ||||
MMP-1 × 10−1 |
23-24 | 66 (18, 171) | 52 (17, 105) | 65 (21, 174) |
25-26 | 59 (20, 150) | 53 (24, 148) | 68 (27, 204) | |
27 | 57 (19, 148) | 69 (20, 173) | 90 (26, 250) | |
MMP-9 × 10−2 |
23-24 | 93 (25, 317) | 173 (55, 659) | 197 (68, 567) |
25-26 | 81 (26, 322) | 141 (51, 430) | 162 (66, 352) | |
27 | 76 (23, 304) | 97 (36, 299) | 126 (47, 294) | |
Inflamed placenta | ||||
MMP-1 × 10−1 |
23-24 | 66 (23, 174) | 47 (22, 103) | 66 (25, 183) |
25-26 | 75 (27, 175) | 58 (27, 169) | 73 (29, 239) | |
27 | 70 (19, 197) | 73 (18, 166) | 98 (28, 278) | |
MMP-9 × 10−2 |
23-24 | 106 (25, 382) | 306 (93, 855) | 196 (99, 638) |
25-26 | 110 (28, 480) | 219 (91, 589) | 159 (65, 309) | |
27 | 126 (26, 589) | 190 (88, 547) | 112 (50, 285) | |
Non-inflamed placenta | ||||
MMP-1 × 10−1 |
23-24 | 64 (14, 167) | 58 (14, 111) | 60 (18, 142) |
25-26 | 46 (16, 114) | 49 (23, 123) | 64 (25, 187) | |
27 | 51 (19, 131) | 66 (20, 181) | 83 (25, 241) | |
MMP-9 × 10−2 |
23-24 | 82 (25, 209) | 114 (41, 405) | 197 (60, 534) |
25-26 | 71 (26, 219) | 95 (37, 302) | 164 (68, 408) | |
27 | 65 (22, 171) | 79 (33, 172) | 131 (45, 297) |