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. Author manuscript; available in PMC: 2010 Nov 18.
Published in final edited form as: J Neurochem. 2006 Jul;98(1):234–247. doi: 10.1111/j.1471-4159.2006.03855.x

Figure 3. Regulation of TIMP-2 expression in Neuro-2a cells.

Figure 3

Cell surface TIMP-2 was not detected on proliferating Neuro-2a cells (10% serum, A-F) or cells differentiated by serum depletion (0.5% serum, M-Q). However, intracellular TIMP-2 was present in both proliferating (G-L) and Triton-permeabilized differentiated cells (R-V). TIMP-2 was even detected in neurites of spontaneously differentiated cells maintained in 10% serum (J, K arrows). In differentiated cells, TIMP-2 was present in both fibrous processes and lamellapodial processes (U). Scale bar = 50 μm.