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. Author manuscript; available in PMC: 2010 Nov 18.
Published in final edited form as: Transplantation. 1990 Mar;49(3):483–490. doi: 10.1097/00007890-199003000-00001

Figure 3.

Figure 3

Postoperative weight change following small intestine transplantation in the rat. A. Fully allogeneic model—progressive weight gain is noted in the FK-506–treated rats (group IIA). Following a several-month period of well-being, chronic rejection resulted in weight loss and death of the animals. Only high doses of CsA (group VII) resulted in weight gain in the recipients. The remaining survivor is alive and thriving at >3 months posttransplantation. B. Semiallogeneic model of rejection after an initial period of slight loss, the surviving FK-506–treated animals gained weight. Control animals lost weight and died in a short period of time. C. Semiallogeneic model of GVHD—the FK-506–treated animals show progressive weight gain. The CsA-treated group gained weight until the late onset of lethal GVHD resulted in weight loss and death.