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Donor small intestine, semiallogeneic rejection model: A. control animal (group IB) at 8 days showing severe rejection with villous blunting, cryptitis, and inflammation (H&E; ×100); and B. FK-506–treated animal (group IIB) at 12 days demonstrating rare singlecell necrosis (arrow) and minimal inflammation (H&E; ×125).
