Fig. 4. D3R signaling does not affect Na+ or K+.
(A) AP train-evoked Na+ influx in the AIS, imaged with SBFI, before (black) and after 1 μM quinpirole (grey). Na+ transients were computed as the change in SBFI fluorescence over baseline.
(B) AP train-evoked Na+ influx in the AIS before (black) and after 1 nM TTX (grey).
(C) Summary of pharmacological effects on AIS Na+. Values normalized to baseline ΔF/F0 amplitudes. Dots are single cells. Error bars are SEM. Asterisk: p < 0.01.
(D) Persistent Na+ currents before (black) and after quinpirole (grey).
(E) K+ currents before (black) and after quinpirole (grey).
(F) K+ current vs. step voltage. Black: baseline. Grey: quinpirole. Data from each condition superimpose. Bars are SEM.
