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. Author manuscript; available in PMC: 2011 Nov 4.
Published in final edited form as: Neuron. 2010 Nov 4;68(3):500–511. doi: 10.1016/j.neuron.2010.09.026

Fig. 4. D3R signaling does not affect Na+ or K+.

Fig. 4

(A) AP train-evoked Na+ influx in the AIS, imaged with SBFI, before (black) and after 1 μM quinpirole (grey). Na+ transients were computed as the change in SBFI fluorescence over baseline.

(B) AP train-evoked Na+ influx in the AIS before (black) and after 1 nM TTX (grey).

(C) Summary of pharmacological effects on AIS Na+. Values normalized to baseline ΔF/F0 amplitudes. Dots are single cells. Error bars are SEM. Asterisk: p < 0.01.

(D) Persistent Na+ currents before (black) and after quinpirole (grey).

(E) K+ currents before (black) and after quinpirole (grey).

(F) K+ current vs. step voltage. Black: baseline. Grey: quinpirole. Data from each condition superimpose. Bars are SEM.