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Representative images showing the extent of aortic atherosclerosis in chow-fed ACAT2+/+ ApoE–/– and ACAT2–/– ApoE–/– mice. (A) Pinned-out aortas showing surface lesions (arrows) in ACAT2+/+ ApoE–/– but not in ACAT2–/– ApoE–/– mice. (B) Cross sections of proximal aortic roots showing Oil-red-O-staining lesions (arrow points to example) in ACAT2+/+ ApoE–/– but not in ACAT2–/– ApoE–/– mice. (Bar = 500 μm.)
