Table 1.

Plasma lipid levels

	ACAT2+/+ApoE−/−	ACAT2−/−ApoE−/−	P
Total cholesterol (TC)	436.6 ± 91.7	179.7 ± 52.4	<0.0001
Cholesterol esters (CE)	284.5 ± 71.3	78.8 ± 19.5	0.0005
Free cholesterol (FC)	130.4 ± 21.7	106.9 ± 18.6	0.028
HDL cholesterol	18.5 ± 5.7	29.8 ± 8.1	0.0019
Triglyceride (TG)	56.7 ± 26.7	108.3 ± 46.0	0.015

Plasma lipids (mg/dl) were measured in adult (20- to 26-week-old) female mice (ACAT2^+/+ ApoE^−/−: TC, n = 10; CE, n = 7; FC, n = 7, HDL, n = 10; TG, n = 9. ACAT2^−/− ApoE^−/−: TC, n = 20; CE, n = 11; FC, n = 12; HDL, n = 16; TG, n = 12). Data are shown as mean ± SD. P values were determined with the Mann–Whitney test.