A representative image of (A) zymographic and densitometric analysis of (B) pro-MMP-9, (C) pro-MMP-2, and (D) active MMP-2. *P = .0259 vs PPE. Representative images of Elastica-Masson-stained aortic cross-sections in (E) PPE (F) and PPE-DM (original magnification ×200), and (G) the ratio of stained-elastin-area to media-area. *P = .0209 vs PPE. DM, Diabetes mellitus; MMP, matrix metalloproteinase; PPE, porcine pancreatic elastase. The range bars show the standard deviation.