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. Author manuscript; available in PMC: 2011 Jul 6.
Published in final edited form as: Biochemistry. 2010 Jul 6;49(26):5511–5523. doi: 10.1021/bi100157u

Figure 5. Membrane bound LRRK2 can be crosslinked more efficiently into HMW complexes than cytosolic LRRK2.

Figure 5

Crosslinking with DSS of endogenous or transfected LRRK2 leads to formation of HMW complexes in membrane fractions (Mem), but not in cytosol (Cyto). Extracts from human lymphoblasts (A), HEK293FT cells transfected with LRRK2 (B), and non-human primate cortex (C) were analyzed.

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