Selective adenosine A1, A2A, and dual antagonist effects on feeding behavior and locomotor activity over 4 h. (A) Food consumption, g/kg body weight (mean ± SEM). (B) Locomotion is reported as distance traveled in meters. Control mice, white bars (n = 4–8); Th−/−; DbhTh/+ mice, black bars (n = 4–8). Numbers indicate dose of drug (mg/kg body weight).