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. 2010 Nov 3;12(1):62. doi: 10.1186/1532-429X-12-62

Figure 7.

Figure 7

Quantitative 19F spectroscopy of angiogenesis in aortic valve disease. The 19F signal was utilized to quantify binding of nanoparticles to the valve leaflets from (A) a rabbit treated with ανβ3-targeted nanoparticles and (B) a rabbit treated with untargeted nanoparticles. Both nanoparticle formulations consisted of a crown ether core, which generates a single peak. The PFOB peaks originated from a reference standard utilized for quantification. Nanoparticle binding in the rabbit treated with targeted particles was much higher (Crown Ether/PFOB = 4.6) than the rabbit treated with nontargeted particles (Crown Ether/PFOB = 2.2). Reprinted with permission from Waters, et al [84].