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. 2010 Nov 1;3:25. doi: 10.1186/1757-1146-3-25

Table 4.

Causes of melanonychia compared with those of subungual bleeding

Melanonychia Subungual bleeding
Benign racial melanonychia Direct trauma
Laugier Hunziker Indirect microtrauma-end on repetitive trauma
Inflammation Haemorrhagic tendency lowering threshold for effects of trauma. eg
 • Lichen planus  • warfarin
 • Chronic paronychia  • leukaemic
 • Trauma/friction  • thrombocytopaenia
 • radiation
Medication e.g. Subungual tumour
 • Minocycline  • squamous cell carcinoma
 • Chemotherapy  • wart
 • HIV disease or medication  • exostosis
 • melanoma
 • pyogenic granuloma
Addison's disease
Peutz Jeghers
Subungual naevus
Benign melanocyte activation
Melanoma
Bowen's disease (in situ squamous cell carcinoma)
Onychomycosis