Table 3.

Genotypic frequencies of the MTHFR C677T and serum lipid levels between the Bai Ku Yao and Han populations

Genotype	n	TC (mmol/L)	TG (mmol/L)	HDL-C (mmol/L)	LDL-C (mmol/L)	ApoAI (g/L)	ApoB (g/L)	ApoAI/ApoB
Bai Ku Yao
CC	458	4.20 ± 0.85	0.97(0.73)	1.62 ± 0.40	2.45 ± 0.70	1.27 ± 3.15	0.82 ± 0.22	1.69 ± 0.81
CT	291	4.33 ± 1.06	0.94(0.68)	1.67 ± 0.44	2.57 ± 0.85a	1.30 ± 3.33	0.84 ± 0.25	1.70 ± 0.77
TT	31	4.52 ± 0.62	1.11(0.68)	1.75 ± 0.40	2.67 ± 0.44a	1.38 ± 0.34	0.86 ± 0.15	1.63 ± 0.40
F	-	2.807	0.932	1.993	3.299	1.884	0.592	0.091
P	-	0.061	0.334	0.137	0.037	0.153	0.554	0.913
CC	458	4.20 ± 0.85	0.97(0.73)	1.62 ± 0.40	2.45 ± 0.70	1.27 ± 0.31	0.82 ± 0.22	1.69 ± 0.81
CT/TT	322	4.34 ± 1.02	0.96(0.68)	1.68 ± 0.43	2.58 ± 0.81	1.31 ± 0.33	0.84 ± 0.24	1.69 ± 0.75
F	-	2.098	0.611	1.722	2.462	1.489	0.942	0.040
P	-	0.036	0.541	0.085	0.014	0.137	0.347	0.968
Male
CC	228	4.20 ± 0.90	1.08(0.78)	1.64 ± 0.45	2.38 ± 0.75	1.32 ± 0.34	0.81 ± 0.22	1.82 ± 1.01
CT	131	4.33 ± 1.27	1.11(0.80)	1.67 ± 0.50	2.54 ± 1.01	1.34 ± 0.40	0.81 ± 0.26	1.87 ± 1.03
TT	22	4.63 ± 0.73	1.02(0.66)	1.80 ± 0.39	2.75 ± 0.54	1.37 ± 0.40	0.88 ± 0.18	1.61 ± 0.44
F	-	2.076	1.005	1.416	2.873	0.258	0.971	0.636
P	-	0.127	0.605	0.244	0.058	0.773	0.379	0.530
CC	228	4.20 ± 0.90	1.08(0.78)	1.64 ± 0.45	2.38 ± 0.75	1.32 ± 0.34	0.81 ± 0.22	1.82 ± 1.01
CT/TT	153	4.37 ± 1.21	1.07(0.80)	1.69 ± 0.48	2.58 ± 0.96	1.35 ± 0.39	0.82 ± 0.25	1.83 ± 0.97
F	-	1.619	0.105	1.108	2.139	0.701	0.536	0.064
P	-	0.106	0.916	0.269	0.033	0.484	0.592	0.949
Female
CC	230	4.21 ± 0.80	0.92(0.69)	1.61 ± 0.35	2.51 ± 0.63	1.23 ± 0.25	0.83 ± 0.20	1.56 ± 0.51
CT	156	4.28 ± 0.83	0.82(0.65)	1.67 ± 0.39	2.57 ± 0.65	1.27 ± 0.25	0.85 ± 0.24	1.50 ± 0.38
TT	13	4.68 ± 0.66	1.65(0.95)ac	1.63 ± 0.34	2.87 ± 0.53	1.36 ± 0.29	0.91 ± 0.14	1.57 ± 0.42
F	-	2.363	9.541	1.024	2.097	2.433	0.841	0.108
P	-	0.095	0.008	0.360	0.124	0.089	0.432	0.897
CC	230	4.21 ± 0.80	0.92(0.69)	1.61 ± 0.35	2.51 ± 0.63	1.23 ± 0.25	0.83 ± 0.20	1.56 ± 0.51
CT/TT	156	4.32 ± 0.82	0.83(0.66)	1.66 ± 0.38	2.59 ± 0.64	1.28 ± 0.26	0.86 ± 0.23	1.56 ± 0.42
F	-	1.344	0.757	1.395	1.210	1.738	0.730	0.019
P	-	0.180	0.449	0.164	0.227	0.083	0.466	0.985
Han Chinese
CC	224	4.56 ± 0.81	0.97(0.73)	1.91 ± 0.52	2.48 ± 0.66	1.40 ± 0.23	0.88 ± 0.20	1.67 ± 0.43
CT	387	4.77 ± 0.95a	1.02(0.79)	1.92 ± 0.48	2.64 ± 0.73a	1.42 ± 0.23	0.92 ± 0.21	1.61 ± 0.41
TT	75	4.88 ± 1.05b	1.02(0.78)	1.93 ± 0.53	2.69 ± 0.80a	1.42 ± 0.25	0.92 ± 0.23	1.65 ± 0.51
F	-	5.003	2.468	0.093	4.218	0.508	2.756	1.214
P	-	0.007	0.288	0.911	0.015	0.602	0.064	0.298
CC	224	4.56 ± 0.81	0.97(0.73)	1.90 ± 0.52	2.48 ± 0.66	1.40 ± 0.23	0.88 ± 0.20	1.67 ± 0.43
CT/TT	462	4.79 ± 0.97	1.02(0.79)	1.92 ± 0.48	2.65 ± 0.74	1.42 ± 0.24	0.92 ± 0.21	1.62 ± 0.43
F	-	3.036	1.538	0.347	2.853	1.007	2.346	1.399
P	-	0.002	0.124	0.708	0.004	0.314	0.019	0.162
Male
CC	107	4.58 ± 0.86	1.03(0.73)	188 ± 0.57	2.45 ± 0.69	1.39 ± 0.26	0.88 ± 0.21	1.66 ± 0.46
CT	199	4.72 ± 0.94	1.02(0.80)	1.85 ± 0.49	2.61 ± 0.69	1.40 ± 0.24	0.91 ± 0.20	1.60 ± 0.41
TT	36	5.08 ± 1.05bc	1.06(0.80)	1.93 ± 0.54	2.79 ± 0.91a	1.43 ± 0.27	0.94 ± 0.24	1.64 ± 0.57
F	-	4.105	0.554	0.328	3.426	0.461	0.991	0.612
P	-	0.017	0.758	0.720	0.034	0.631	0.372	0.543
CC	107	4.58 ± 0.86	1.03(0.73)	188 ± 0.57	2.45 ± 0.69	1.39 ± 0.26	0.88 ± 0.21	1.66 ± 0.46
CT/TT	235	4.77 ± 0.96	1.02(0.80)	1.87 ± 0.50	2.64 ± 0.73	1.40 ± 0.25	0.91 ± 0.21	1.61 ± 0.44
F	-	1.807	0.710	0.168	2.160	0.188	1.128	0.966
P	-	0.072	0.478	0.867	0.032	0.851	0.260	0.335
Female
CC	117	4.55 ± 0.76	0.92(0.74)	1.93 ± 0.46	2.50 ± 0.61	1.41 ± 0.19	0.87 ± 0.19	1.68 ± 0.41
CT	188	4.81 ± 1.02a	1.00(0.76)	1.98 ± 0.45	2.65 ± 0.78	1.44 ± 0.24	0.93 ± 0.22	1.63 ± 0.42
TT	39	4.80 ± 0.72	0.97(0.76)	1.97 ± 0.47	2.64 ± 0.62	1.44 ± 0.16	0.91 ± 0.19	1.65 ± 0.45
F	-	3.091	1.704	0.377	1.802	1.002	2.487	0.537
P	-	0.047	0.427	0.687	0.167	0.368	0.085	0.585
CC	117	4.55 ± 0.76	0.92(0.74)	1.93 ± 0.46	2.50 ± 0.61	1.41 ± 0.19	0.87 ± 0.19	1.68 ± 0.41
CT/TT	227	4.81 ± 0.97	1.00(0.76)	1.98 ± 0.45	2.65 ± 0.72	1.44 ± 0.23	0.92 ± 0.21	1.63 ± 0.42
F	-	2.489	1.288	0.864	1.892	1.400	2.191	0.979
P	-	0.013	0.198	0.388	0.059	0.162	0.029	0.328

TC, total cholesterol; TG, triglyceride; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; ApoAI, apolipoprotein AI; ApoB, apolipoprotein B; ApoAI/ApoB, the ratio of apolipoprotein AI to apolipoprotein B. The value of TG was presented as median (interquartile range). The difference in serum TG levels was determined by the Kruskal-Wallis test or the Wilcoxon-Mann-Whitney test. ^aP < 0.05 and ^bP < 0.05 in comparison with CC genotype and ^cP < 0.05 in comparison with CT genotype in the same group