Table 7.

Group 2 (Investigators) (n = 24) - Testing performed at each Laboratory

	Archway (75 m)	Kathmandu (1300 m)	Namche (3500 m)	Pheriche (4280 m)	EBC (I) (5300 m)	EBC (II) (5300 m)	Camp 2 (6400 m)	South Col (7950 m)
Subjects at laboratory	24	24	24	24	24	23	14	12
CORE STUDIES
Daily diary	24	24	24	24	24	23	14	5
CPX Ramp (+muscle and brain NIRS)[17]	24	24	22	24	23	22	14	5
CPX ME	24	24	23	n/a	24	23	14	n/a
Spirometry	24	24	24	23	23	23	14	6
Venesection	24	24	24	24	24	23	14	n/a
Neurocognitive	21	21 (on return)	21	21	21	n/a	13	6
Pupillometry	24	24	24	20	24	23	14	0
Cranial measurement	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Retinal Photography	24	n/a	n/a	n/a	24	23	n/a	n/a
Plasma biomarkers	24	24	24	24	24	23	n/a	n/a
ADDITIONAL STUDIES
Arterial Blood Gases[25]	10	n/a	n/a	n/a	9	n/a	9	n/a
Gastric Tonometry	10	n/a	n/a	n/a	n/a	9	n/a	n/a
Cardiac Output	10	n/a	n/a	n/a	n/a	9	n/a	n/a
Microcirculation[24]	24	n/a	24	n/a	24	23	14	4
Weight & Body comp	24	24	24	24	24	23	13	n/a
Muscle Biopsy	20	n/a	n/a	n/a	n/a	18	n/a	n/a
ECG	19	19	19	19	19	19	n/a	n/a
Oxygen circuit	n/a	n/a	n/a	n/a	n/a	n/a	5	n/a
Smell and taste	24	n/a	n/a	n/a	n/a	24	n/a	n/a
Thromboelastography	17	n/a	n/a	17	n/a	14	n/a	n/a
Cerebral Doppler	24	24	24	24	24	24	13	5
Saccadometry	22	22	22	22	22	22	12	n/a
Cardiac MRI and 31P-MRS	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Skeletal Muscle MRI and 31P-MRS	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a
MR Brain structural and volumetric studies	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a