Table 3.
Correlation between VLDLR II expression and clinical features in 46 Breast cancer patients
| Parameters | Number | VLDLR II fold | P |
|---|---|---|---|
| Age at diagnosis | |||
| ≥ 50 years | 29 | 1.30 ± 0.44 | 0.820 |
| < 50 years | 17 | 1.28 ± 0.40 | |
| Body weight | |||
| ≥ 50 kg | 19 | 1.38 ± 0.39 | 0.080 |
| < 50 kg | 27 | 1.21 ± 0.43 | |
| TC | |||
| > 5.20 mmol/L | 7 | 1.09 ± 0.34 | 0.178 |
| ≤ 5.20 mmol/L | 39 | 1.31 ± 0.42 | |
| TG | |||
| > 1.70 mmol/L | 13 | 1.15 ± 0.28 | 0.360 |
| ≤ 1.70 mmol/L | 33 | 1.33 ± 0.45 | |
| Histological grade | |||
| Well to moderately differentiated | 28 | 1.18 ± 0.36 | 0.043* |
| Poorly differentiated | 18 | 1.43 ± 0.45 | |
| Tumor size | |||
| ≥ 2 cm | 21 | 1.34 ± 0.47 | 0.442 |
| < 2 cm | 25 | 1.22 ± 0.37 | |
| Lymph node metastasis | |||
| Negative | 15 | 1.14 ± 0.15 | 0.003* |
| Positive | 31 | 1.43 ± 0.45 | |
| Distant metastasis | |||
| Negative | 32 | 1.16 ± 0.30 | 0.007* |
| Positive | 14 | 1.52 ± 0.41 | |
| TNM stage | |||
| Stage I-II | 24 | 1.14 ± 0.31 | 0.027* |
| Stage III-IV | 22 | 1.41 ± 0.47 |
Folds (VLDLR II protein in tumor/in normal) in mean ± SD. VLDLR II measured by Western blot. TC, total cholesterol (normal range: ≤ 5.20 mmol/L); TG, triglycerides (normal range: ≤ 1.70 mmol/L). Statistical analyses were performed by Mann-Whitney test.
* P < 0.05 is considered significan