Skip to main content
. Author manuscript; available in PMC: 2011 Dec 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2010 Sep 9;30(12):2535–2543. doi: 10.1161/ATVBAHA.110.214379

Figure 7. Increased COX 2 expression in Bmal1-KO endothelial cells.

Figure 7

Mouse aortic endothelial and smooth muscle cells were isolated from Bmal1-KO and WT mice (see methods). Isolated cells were cultured and protein lysates were isolated and separated by SDS-PAGE electrophoresis. (A) Expression levels of COX-2 but not COX-1 were significantly increased in endothelial cells from Bmal1-KO mice. (B) COX-2 and COX -1were not significantly different in isolated smooth muscle cells from Bmal1-KO and WT control mice. Changes were quantified by densitometry (*p<0.05 versus WT; N=6)