Fig. 1.

Overview of purine metabolism in human erythrocytes (straight line) and out of them (dotted line). Based on Simmonds et al. 1988 and Smolenski et al. 1991, 1992. ADA adenosine deaminase (EC 3.5.4.4), AK adenosine kinase (EC 2.7.1.20), AMPD AMP deaminase (EC 3.5.4.6), APRT adenine phosphoribosyltranferase (EC 2.4.2.7), cN-I cytosolic AMP-specific 5′-nucleotidase (EC 3.2.3.5), cN-II cytosolic IMP and GMP-specific 5′-nucleotidase (EC 3.2.3.5), GK guanosine kinase (EC 2.7.1.73), HGPRT hypoxanthine-guanine phosphorybosyltransferase (EC 2.4.2.8), IK inosine kinase (EC 2.7.1.73), MTAdo methylothioadenosine, 5′-NT-5′-nucleotidase (EC 3.1.3.5), PNP purine nucleoside phosphorylase (EC 2.4.2.1), PRPP 5′-phosphoribosyl 1-pyrophosphate, SAH S-adenosylhomocysteine, SAHH S-adenosylhomocysteine hydrolase (EC 3.3.1.1), SAM S-adenosylmethionine