Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Mutagenesis of full-length p53 at codon 269 attenuates DO-12 binding. H1299 cells were transfected with pExpr expression vectors encoding p53, p53S269A, or p53S269D mutants, and the proteins were examined for reactivity toward DO-1 (A; total p53), DO-12 (B; epitope 255–270), or PAb240 (C; epitope 209–214) by immunoblotting.
