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. Author manuscript; available in PMC: 2011 Oct 8.
Published in final edited form as: J Mol Biol. 2010 Aug 14;402(5):847–864. doi: 10.1016/j.jmb.2010.08.018

Fig. 3.

Fig. 3

Study of binding mode. CD titration for TTAA in (a) DB293, (b) DB832, (c) DB1003, and AATT in (d) DB1003. The concentration of duplex hairpin was 5 μM and the compound was added with 1 μM increment with total of 10 increments. In case of DB293 and DB1003 in TTAA, DNA saturates at 2:1 compound to DNA ratio confirming dimer formation for these compounds. DB832 in TTAA and DB1003 in AATT with similar compound to DNA ratio give weaker binding.