Table 2.
Biomarkers of iron stores (means±s.e.m., or for ferritin median (interquartile range)) before and 4 h after administration of iron sucrose or placebo
| Iron sucrose (n=20) |
Placebo (n=20) |
||||
|---|---|---|---|---|---|
| Before | 4 h post | Before | 4 h post | P-value* | |
| Serum iron (μM) | 14±2 | 53±11 | 12±1 | 16±1 | 0.001 |
| Total iron binding capacity (μM) | 48±3 | 60±11 | 49±3 | 51±3 | 0.36 |
| % transferrin saturation | 31±9 | 87±9 | 24±2 | 32±2 | <0.001 |
| NTBI (μM) | 0.51±0.09 | 2.54±0.21 | 0.64±0.11 | 0.66±0.09 | <0.001 |
| Serum ferritin (ng/ml) | 93 (113) | 92 (213) | 89 (111) | 81 (117) | 0.84 |
P-value for treatment group-by-time interaction term in repeated measures analysis of variance model.