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. 2010 May 5;30(18):6387–6397. doi: 10.1523/JNEUROSCI.0764-10.2010

Figure 10.

Figure 10.

Model of cortico-striato-thalamic and mesolimbic circuit dysfunction underlying the aberrant generation of repetitive behaviors. Aberrant repetitive behaviors manifest when association cortico-striato-thalamic circuits are reinforced by a loss of FrA inhibitory control, decreased voluntary motor control, and increased VTA-mediated saliency/reward expectancy value.