Figure 7. Human islet SK channels regulate glucose stimulated electrical activity.

A, Western blot analysis of three independent islet preparations with an SK3 specific antibody. B, human β-cell current recorded at −60 mV (top trace) during photolysis of caged calcium with the indicated pulse of 360 nm light (grey line). C, two representative human islet glucose induced β-cell electrical responses to 100 nm apamin (black line).