Figure 3. JNK inhibition ameliorates CCl4-induced hepatic fibrosis.
A–E. SP600125- treated (n=9) and vehicle-treated (n=9) Balb/c mice received 4 gavages of CCl4. Hepatic fibrosis and injury were evaluated by Sirius Red staining (A), αSMA immunohistochemistry (B), αSMA immunoblotting (C), hydroxyproline content (D) and ALT levels 48h after the last CCl4 injection (E). * p<0.05