FIG. 1.

(A and B) The absence of Grx4 increases cell sensibility to hydrogen peroxide and its overexpression induces cell resistance against the oxidizing agent. All of these effects occur independently of Aft1. The following strains were exponentially grown in SD medium plus amino acids before being serial diluted and spotted onto plates either containing, or not containing, 1 mM H₂O₂. The plates were incubated at 30°C for 3 days. (C) Same as in panels A and B, except that the plates contained 1.75 mM hydrogen peroxide. wt, wild type.