Table 3.
Adjusted Domain Scores by Group and Across Assessment Time Points
| Variable by Time Point | Control |
Chemotherapy |
No Chemotherapy |
|||
|---|---|---|---|---|---|---|
| Mean | SD | Mean | SD | Mean | SD | |
| Baseline | ||||||
| No. of patients | 44 | 60 | 72 | |||
| Processing speed | −0.05 | 0.59 | −0.18 | 0.56 | −0.26 | 0.66 |
| Verbal ability | −0.03 | 0.70 | −0.21 | 1.00 | −0.23 | 0.85 |
| Verbal memory | −0.04 | 0.75 | −0.25 | 0.93 | −0.20 | 0.91 |
| Visual memory | −0.04 | 0.91 | −0.10 | 0.93 | 0.01 | 0.80 |
| Working memory | −0.01 | 0.92 | −0.29 | 1.40 | −0.45 | 1.26 |
| Sorting | −0.07 | 0.72 | −0.18 | 0.56 | −0.05 | 0.95 |
| Distractibility | −0.01 | 0.90 | −0.01 | 0.91 | −0.04 | 1.00 |
| Reaction time | −0.02 | 0.88 | −0.77 | 1.17 | −0.28 | 0.90 |
| Block design | −0.02 | 0.91 | −0.21 | 0.94 | −0.29 | 0.89 |
| 1 month after treatment | ||||||
| No. of patients | 43 | 55 | 68 | |||
| Processing speed | 0.12 | 0.58 | −0.11 | 0.46 | −0.14 | 0.65 |
| Verbal ability | 0.12 | 0.58 | −0.23 | 0.53 | −0.15 | 0.73 |
| Verbal memory | 0.45 | 0.72 | 0.15 | 0.86 | 0.09 | 0.87 |
| Visual memory | 0.67 | 0.96 | 0.77 | 0.68 | 0.63 | 0.85 |
| Working memory | 0.33 | 0.96 | 0.24 | 0.86 | 0.03 | 0.99 |
| Sorting | 0.26 | 0.68 | 0.12 | 0.91 | −0.05 | 0.95 |
| Distractibility | 0.28 | 0.47 | 0.12 | 0.47 | −0.04 | 1.00 |
| Reaction time | 0.07 | 0.97 | −0.47 | 1.07 | −0.28 | 0.90 |
| Block design | 0.14 | 0.75 | −0.11 | 0.89 | −0.13 | 0.91 |
| 6 months after treatment | ||||||
| No. of patients | 42 | 49 | 67 | |||
| Processing speed | 0.17 | 0.61 | −0.08 | 0.45 | −0.17 | 0.64 |
| Verbal ability | 0.14 | 0.59 | 0.03 | 0.92 | −0.06 | 0.78 |
| Verbal memory | 0.67 | 0.73 | 0.53 | 0.80 | 0.33 | 0.91 |
| Visual memory | 0.98 | 0.71 | 0.97 | 0.65 | 0.83 | 0.82 |
| Working memory | 0.65 | 0.82 | 0.39 | 0.76 | 0.28 | 0.96 |
| Sorting | 0.39 | 0.75 | 0.40 | 0.90 | 0.26 | 0.89 |
| Distractibility | 0.38 | 0.29 | 0.13 | 0.49 | −0.05 | 1.09 |
| Reaction time | 0.15 | 0.82 | −0.39 | 0.94 | −0.26 | 0.89 |
| Block design | 0.14 | 0.79 | 0.01 | 0.79 | −0.20 | 0.99 |
| 18 months after treatment | ||||||
| No. of patients | 39 | 46 | 64 | |||
| Processing speed | 0.25 | 0.52 | −0.01 | 0.45 | −0.09 | 0.65 |
| Verbal ability | 0.17 | 0.71 | 0.17 | 0.87 | −0.04 | 0.73 |
| Verbal memory | 0.69 | 0.69 | 0.68 | 0.80 | 0.38 | 0.93 |
| Visual memory | 1.05 | 0.80 | 1.04 | 0.69 | 1.02 | 0.71 |
| Working memory | 0.64 | 0.92 | 0.69 | 0.65 | 0.44 | 0.95 |
| Sorting | 0.55 | 0.73 | 0.52 | 0.91 | 0.21 | 0.86 |
| Distractibility | 0.16 | 0.81 | 0.20 | 0.45 | −0.02 | 1.05 |
| Reaction time | 0.16 | 0.88 | −0.57 | 1.14 | −0.28 | 0.95 |
| Block design | 0.18 | 0.76 | 0.11 | 0.84 | −0.07 | 0.82 |
NOTE. Analyses adjusted for age, education, and baseline score.
Abbreviation: SD, standard deviation.