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. Author manuscript; available in PMC: 2011 Dec 15.
Published in final edited form as: J Biomed Mater Res A. 2010 Sep 28;95(4):1159–1169. doi: 10.1002/jbm.a.32942

Figure 6.

Figure 6

(A) Analysis of gelatinase activity in subcutaneous tissue following implantation of PEG:dextran variants. In situ zymography with an internally quenched FITC-labeled gelatin substrate indicated gelatinase activity. Scale bar = 1000 μm and applies to all images. (B) L-DOPA conjugation within PEG:dextran stimulated local tissue gelatinase activity as indicated by a monotonic rise of relative fluorescent measurements with increasing L-DOPA concentration. Error bars represent 1 standard error of measurement (n = 4 to 5). * indicates p < 0.05 determined by ANOVA with post hoc analysis when compared with unmodified PEG:dextran