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. Author manuscript; available in PMC: 2010 Nov 19.
Published in final edited form as: Aging Cell. 2009 Sep 30;8(6):765–768. doi: 10.1111/j.1474-9726.2009.00527.x

Table 1.

Results of different experiments on the effect of oxaloacetate on lifespan

Strain Median lifespan (days ± SEM) Difference (%) n P-value Max lifespan (days ± SEM) Difference (%)


Crtl Exptl Crtl Exptl
N2 control 14.4 ± 0.9 18.0 ± 2.0 +25 5 ≪ 0.001 23.6 ± 3.2 26.4 ± 3.2 +13
N2 control§ 12.5 ± 0.7 14.4 ± 1.1 +15 3 < 0.05 29.0 ± 1.0 31.5 ± 0.5 +5
SIR-2.1 mutant 13.9 ± 3.6 16.2 ± 4.0 +16 2 < 0.01 19.5 ± 4.5 25.0 ± 7.0 +27
DAF-16 mutant 15.0 ± 0.3 13.4 ± 1.0 −11 3 < 0.05 22.0 ± 3.0 22.5 ± 2.5 +3
AAK-2 mutant 11.9 ± 0.2 12.1 ± 0.3 +1 3 1.00 16.7 ± 0.7 14.7 ± 0.3 −5

Comparisons were made between groups treated with 0 (Crtl) or 8 mm (Exptl) oxaloacetate.

Probability (P-value) of no significant difference in median lifespan between control and experimental groups; the P-value given is the higher one of that determined by a single anova test or by Fisher's combined probability test of log rank data.

§

Dead bacteria were used instead of live bacteria. n, number of repeats for a given experiment.