Table 1.
Strain | Median lifespan (days ± SEM) | Difference (%) | n | P-value‡ | Max lifespan (days ± SEM) | Difference (%) | ||
---|---|---|---|---|---|---|---|---|
Crtl | Exptl | Crtl | Exptl | |||||
N2 control | 14.4 ± 0.9 | 18.0 ± 2.0 | +25 | 5 | ≪ 0.001 | 23.6 ± 3.2 | 26.4 ± 3.2 | +13 |
N2 control§ | 12.5 ± 0.7 | 14.4 ± 1.1 | +15 | 3 | < 0.05 | 29.0 ± 1.0 | 31.5 ± 0.5 | +5 |
SIR-2.1 mutant | 13.9 ± 3.6 | 16.2 ± 4.0 | +16 | 2 | < 0.01 | 19.5 ± 4.5 | 25.0 ± 7.0 | +27 |
DAF-16 mutant | 15.0 ± 0.3 | 13.4 ± 1.0 | −11 | 3 | < 0.05 | 22.0 ± 3.0 | 22.5 ± 2.5 | +3 |
AAK-2 mutant | 11.9 ± 0.2 | 12.1 ± 0.3 | +1 | 3 | 1.00 | 16.7 ± 0.7 | 14.7 ± 0.3 | −5 |
Comparisons were made between groups treated with 0 (Crtl) or 8 mm (Exptl) oxaloacetate.
Probability (P-value) of no significant difference in median lifespan between control and experimental groups; the P-value given is the higher one of that determined by a single anova test or by Fisher's combined probability test of log rank data.
Dead bacteria were used instead of live bacteria. n, number of repeats for a given experiment.