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. 2010 Oct 30;8:106. doi: 10.1186/1479-5876-8-106

Table 2.

Combinations of positive/negative phenotypes in a 5-marker panel.

Number of markers
(M)
Number of +/- gates given M markers
(G)
Combinations Number of combinations of M markers in a 5 marker panel (C) Number of gates times number
of combinations
(G × C)
0 20 = 1 No markers specified 1 1

1 21 = 2 A, B, C, D, E 5 10

2 22 = 4 AB, AC, AD, AE, BC, BD, BE, CD, CE, DE 10 40

3 23 = 8 ABC, ABD, ABE, ACD, ACE, ADE, BCD, BCE, BDE, CDE 10 80

4 24 = 16 ABCD, ABCE, ABDE, ACDE, BCDE 5 80

5 25 = 32 ABCDE 1 32

TOTAL = 243

This table illustrates the total number of positive/negative gates in a 5-marker panel, with hypothetical markers A, B, C, D and E. There are five possible 1-marker combinations, ten 2-marker combinations, ten 3-marker combinations, five 4-marker combinations, and one 5-marker combination. For each combination, there are 2M positive/negative gates where M is the number of markers in the combinations. Thus, there are 243 possible phenotypes in a 5 marker experiment. This generalizes to 3M.