Table 2.
Association between TopIIα and Ki67 expression and clinical variables
| Clinical variables | TopIIα expression (%) | P | Ki67 expression (%) | P | ||
|---|---|---|---|---|---|---|
| High | Low | High | Low | |||
| Sex | ||||||
| Male | 25 (22.5) | 86 (77.5) | 0.998 | 39 (35.1) | 72 (64.9) | 0.584 |
| Female | 9 (22.5) | 31 (77.5) | 16 (40.0) | 24 (60.0) | ||
| Smoking status | ||||||
| No | 16 (24.6) | 49 (75.4) | 0.591 | 25 (38.5) | 40 (61.5) | 0.651 |
| Yes | 18 (20.9) | 68 (79.1) | 30 (34.9) | 56 (65.1) | ||
| Histology | ||||||
| Adenocarcinoma | 14 (23.7) | 45 (76.3) | 0.775 | 22 (37.3) | 37 (62.7) | 0.860 |
| Non- adenocarcinoma | 20 (21.7) | 72 (78.3) | 33 (35.9) | 59 (64.1) | ||
| Stage | ||||||
| I | 10 (18.5) | 44 (81.5) | 0.177 | 13 (24.1) | 41 (75.9) | 0.034* |
| II | 15 (31.9) | 32 (68.1) | 23 (48.9) | 24 (51.1) | ||
| III | 9 (18.0) | 41 (82.0) | 19 (38.0) | 31 (62.0) | ||
| T stage | ||||||
| T1 | 13 (34.2) | 25 (65.8) | 0.148 | 18 (47.4) | 20 (52.6) | 0.168 |
| T2 | 18 (18.2) | 81 (81.8) | 34 (34.3) | 65 (65.7) | ||
| T3-4 | 3 (21.4) | 11 (78.6) | 3 (21.4) | 11 (78.6) | ||
| N stage | ||||||
| N0 | 12 (19.4) | 50 (80.6) | 0.137 | 16 (25.8) | 46 (74.2) | 0.065 |
| N1 | 16 (32.0) | 34 (68.0) | 23 (46.0) | 27 (54.0) | ||
| N2 | 6 (15.4) | 33 (84.6) | 16 (41.0) | 23 (59.0) | ||
* P < 0.05 was considered statistically significant