Table 5.

Multivariate analysis for factors related to DFS using the COX proportional hazard model

Factors	Wald	Hazard ratio	95% CI	P
Sex	0.903	0.784	0.474 - 1.295	0.342
Histology(adenocarcinoma)	11.277	2.140	1.373 - 3.337	0.001*
TNM stage (later)	14.631	1.688	1.291 - 2.208	<0.001*
Topoisomerase II alpha expression (high expression)	6.773	0.442	0.239 - 0.818	0.009*

* P < 0.05 was considered statistically significant