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. Author manuscript; available in PMC: 2010 Nov 19.
Published in final edited form as: Biochem Pharmacol. 2007 Nov 22;75(5):1129–1160. doi: 10.1016/j.bcp.2007.11.006

Figure 3. An overview of the strategy to select differentially expressed genes.

Figure 3

Beginning with all Affymetrix IDs on the MG-430 2.0 GeneChip (45037 genes), the first filter selected the genes with a “Present” call in at least 3 microarrays. The second step filtered out statistically insignificant means based on the Welch’s t- test. The third step filtered out genes with less than a 2-fold difference in expression between the two conditions.