Table 3.
Release of AA by neutrophils
Neutrophils [3H]AA release (%) Mean ± SD (n) | ||
---|---|---|
NT | GM-CSF | |
CT a | 6.3 ± 4.8 (16) | 10.8 ± 5.7 (16)b |
CF | 4.1 ± 3.3 (15) | 5.4 ± 2.0 (15) |
a CT: NT vs GM-CSF, p < 0.01
b GM-CSF: CT vs CF, p < 0.02.
The release of [3H]AA into the medium by neutrophils isolated from control subjects (CT) and patients with cystic fibrosis (CF) was measured in resting cells (NT) and after stimulation with GM-CSF (0.2 nM). Data are expressed as a percentage of the total radioactivity incorporated into the cells.