Figure 3. Alignment between the PfCRT family and the DUF914 family.

Profile-profile alignment of PfCRT homologs (see Materials and Methods) and the Pfam family DUF914, a member of the DMY clan. Residues are colored according to their physico-chemical properties (green = hydrophobic, red = negatively charged, blue = positively charged, pink = polar, white = small, yellow = cysteine, gray = proline, orange = histidine). The image was generated using the MPI Bioinformatics Toolkit [52].