Table 3. Values of the parameters used throughout the paper.
Parameter | Description | Value | Reference |
Cout = Ce | external chloroquine concentration | 2 nM | [29] |
k1 | chloroquine dissociation constants | 10−8.1 | [53] |
k2 | chloroquine dissociation constants | 10−10.2 | [53] |
Vin | volume of the erythrocyte | 80 fL | [10] |
VDV | volume of the vacuole | 4 fL | [10] |
Pcq | vacuole membrane permeability | 7.5 cm/s | [54] [55] |
pHe | external (physiological) pH | 7.4 | [29] |
pHDV | vacuole pH | 4.5–4.95.18±0.055.4–5.5 | [36] [37] [38] |