Figure 2. Analysis of gene order shows the recent acquisition of pin-c in the het-c region in Neurospora/Sordaria.

Bars indicate genes and are not drawn to scale. Arrows indicate gene orientation. Lines connect genes that are immediate neighbors on a chromosome or contig. Colored boxes indicate homologous genes as determined by sequence conservation and conserved gene order. Genes not connected to lines are found on a different chromosome or contig than the rest and are therefore unlinked. ‘X’ indicates genome rearrangement break points or indicates presence of intervening gene(s) (not shown). The het-c/pin-c (NCU03493/NCU03494) region in S. macrospora has undergone a gene duplication and rearrangement [29], resulting in one full and one partial het-c paralogs and two complete and divergent pin-c paralogs. The cladogram to the left represents the evolutionary relationship between species and is derived from James et al. [90]. Estimated divergence times are derived from Taylor and Berbee [34].