Histology of thymic biopsy (HE). A) Thymus of 29 month-old male pig # 15630 prior to Lupron injection (a), 1 month (b), 2 months (c), 3 months after (e) and 6 months after injection. B and C) Thymus of 22 month-old male pigs # 15959 and 16254 respectively prior to Lupron injection (a), 1 month (b), 2 months (c), 3 months after (e), and 6 months after injection. Animals #15630 and #16254 had increased atrophy at 1 month, but all animals had rejuvenation of thymic architecture at 2 months that was durable until 6 months after Lupron injection.