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. Author manuscript; available in PMC: 2011 Dec 1.
Published in final edited form as: Alcohol Clin Exp Res. 2010 Sep 22;34(12):2070–2080. doi: 10.1111/j.1530-0277.2010.01303.x

Figure 2. Acute ethanol administration reduces the in vivo recorded spontaneous firing rate of Purkinje neurons from adult rats without altering the spontaneous firing rate of Purkinje neurons from adolescent rats.

Figure 2

(A) Mean spontaneous firing rates of cerebellar Purkinje neurons from adolescent and adult animals during the course of an acute ethanol administration, expressed as a percentage of baseline spontaneous activity. Overall a significant difference in the firing rate was found that was dependent on the age of the subject. The spontaneous firing rate of a single representative Purkinje neuron from (B) an adult animal and (C) an adolescent animal prior to, during, and 30 minutes after a 1.5 g/kg ethanol administration. Error bars denote S.E.M.