Fig. 11.

Estimated volumes of brain structures in normal volunteers are plotted against age. The volumes in the figures are presented as standardized residuals (removing variability associated with volume of the supratentorial cranial vault). They are, from left, volumes of frontal cortex, thalamus, nucleus accumbens, and cerebral white matter. Note the rapid age-related change (and striking individual differences) in the childhood and adolescent age-range. (Figures modified from Jernigan & Gamst, Neurobiology of Aging, 26 (9), 1271–1274, 2005)