Figure 3. Distribution of seizure stages during the initial and later seizure clusters.

The number (fractional distribution) of seizures within each seizure stage was determined by randomized sampling for the initial cluster (A) and all of the later clusters combined (B) in the depth-electrode implanted, MSO-treated animals. The fractional distribution of seizures at different stages is indicated by boxplots and vertical point plots (which are superimposed on the boxplots). Each data point (black dot) represents the average number of seizures from one animal. The median number of Stage I seizures is significantly higher than the median number of seizures of any other stage during the initial cluster (p < 0.001, Kruskal-Wallis analysis followed by Dunn’s test, n = 16). See the legend to Fig. 2 for an explanation of the plots.