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. Author manuscript; available in PMC: 2010 Nov 20.
Published in final edited form as: Hum Mutat. 2009 Aug;30(8):1167–1174. doi: 10.1002/humu.21017

Figure 2. Somatic mutations of plexin genes in melanoma and PDAC.

Figure 2

Chromatograms of two of the seven somatic mutations found in plexin genes in different melanomas and PDAC (other mutations are shown in Supp. Figure S3 and S4). PLXNA4 p.H1736Y mutation was found in melanoma sample 14A, while PLXNB3 p.R538H was identified in PDAC sample 384. In both cases, the lower chromatogram is from the tumor sample, and the upper chromatogram is from the corresponding normal. Arrows indicate the location of missense somatic mutations, and the nucleotide and amino acid alterations are indicated below the traces. Numbers above the sequences are part of the software output.