Fig. 5.

Morphometric evaluation of immunohistochemical reaction results for pan-CK, CK-18 and Galectin-3 in the autopsy series. The histogram shows the distribution of negative/positive cells and the extent of positive staining in the four age groups, juvenile/adolescent (0–17 years), young adult (18–30 years), mature adult (31–60 years) and elderly age group (≥60 years). Categorization: − no reaction, + few labeled cells, i.e. <10% of cells stained, ++ intermediate amount of stained cells with 10–50% of cells stained, +++ numerous labeled cells, i.e. >50% of cells stained