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. Author manuscript; available in PMC: 2010 Nov 21.
Published in final edited form as: Cell. 1997 Jun 27;89(7):1067–1076. doi: 10.1016/s0092-8674(00)80294-9

Figure 5. Daxx Activates the JNK Pathway.

Figure 5

(A) Daxx activates JNK in transient transfection. Flag-tagged JNK1 (Flag-JNK) and the indicated plasmids (1 μg each) were cotransfected into 293 cells. Top: phosphorylation of GST-cJun. Bottom: expression of Flag-JNK. The data shown are representative of four independent assays.

(B) Stable expression of Daxx constitutively activates JNK. Top: phosphorylation of GST-cJun. Bottom: expression of endogenous JNK. The data shown are representative of three independent assays.

(C) Daxx activates a JNK-dependent reporter gene. The data shown are the average and SD of three independent experiments in duplicate.