Table 4.

A comparison between patients with vascular events due to atherosclerosis to patients with vascular events due to SLE.

	Patients with vascular events due to AS	Patients with vascular events due to SLE	P value
No. of patients*	22	42
Caucasian	17 (77.3%)	21 (50.0%)	0.03
Male	9 (40.9%)	8 (19.1%)	0.06
Age at Diagnosis	54.6 ± 13.1	41.2 ± 13.8	0.0004
Hypertension	14 (63.6%)	28 (66.7%)	0.81
Obese (BMI >27 F >25 M)	12 (57.1%)	15 (36.6%)	0.12
Diabetes mellitus	2 (10.5%)	1 (2.4%)	0.23
Smoker (Current or Ex)	14 (63.6%)	16 (38.1%)	0.052
Family Hx CAD (adjusted for age) **	9 (42.9%)	13 (31.7%)	0.39
Hypercholesterolemia	12 (54.6%)	19 (45.2%)	0.48
Antiphospholipid Ab at enrolment***  ACL  LAC	8/20 (40.0%) 3/17 (17.7%) 6/20 (30.0%)	15/35 (42.9%) 5/32 (15.6%) 14/35 (40.0%)	0.84 1.00 0.46
Corticosteroids	17 (77.3%)	30 (71.4%)	0.62
Antimalarials	16 (72.7%)	15 (36.6%)	0.006
Immunosuppressive drug use	6 (27.3%)	21 (50.0%)	0.08
SLEDAI-2K	3.32 ± 3.09	5.93 ± 7.47	0.43
AMS at Year 2	3.02 ± 3.11	4.91 ± 4.82	0.15

^*There were 31 atherosclerotic vascular events in 22 patients, and 50 vascular events due to SLE in 42 patients.

^**first degree relative Female < 65 years old or Male < 55 years old.

^***anticardiolipin antibody or lupus anticoagulant AMS=adjusted mean SLEDAI-2K