Table 4.

The effect of adjustment for BMI at 7 years, and BMI at 11 years, on relationship between onset of puberty and cholesterol, and lipids and BMI at age 53 years

	Unadjusted		Adjusted for BMI age 7 years		Adjusted for BMI aged 11 years
Outcome	Regression coefficienta(95% CI)	p	Regression coefficienta(95% CI)	p	Regression coefficienta(95% CI)	p
Women
Triglycerides (%)b	−2.61 (−5.41, 0.50)	.07	−2.60 (−5.4, 0.30)	.08	−1.83 (−4.84, 1.21)	.24
Cholesterol, mmol/L	−0.05 (−0.11, 0.02)	.14	−0.05 (−0.11, 0.01)	.11	−0.05 (−0.11, 0.02)	.15
LDL, mmol/L	−0.03 (−0.09, 0.02)	.29	−0.04 (−0.10, 0.02)	.19	−0.03 (−0.09, 0.02)	.25
HDL, mmol/L	0.02 (−0.01, 0.04)	.24	0.01 (−0.01, 0.04)	.33	−0.01 (−0.02, 0.04)	.44
BMI, kg/m2	−0.75 (−1.00, –0.48)	<.001	−0.52 (−0.79, –0.25)	<0.001	−0.23 (−0.50, 0.04)	.09
Men
Triglycerides, %b	−0.60 (−4.7, 3.5)	.77	−0.70 (−3.8, 2.3)	.64	−0.50 (−4.6, 3.7)	.83
Cholesterol, mmol/L	−0.01 (−0.08, 0.06)	.82	−0.02 (−0.09, 0.06)	.66	−0.02 (−0.09, 0.05)	.63
LDL, mmol/L	0.03 (−0.04, 0.10)	.41	0.03 (−0.04, 0.10)	.39	0.02 (−0.05, 0.09)	.58
HDL, mmol/L	−0.01 (−0.04, 0.02)	.56	−0.01 (−0.04, 0.02)	.44	−0.01 (−0.05, 0.02)	.38
BMI, kg/m2	−0.43 (−0.69, –0.18)	<.001	−0.34 (−0.59, –0.09)	.01	−0.22 (−0.46, 0.03)	.08

BMI = body mass index; HDL = high-density lipoprotein; LDL = low-density lipoprotein.

^aRegression coefficients represent mean change per year increase in age at menarche in women and mean change per group increase in men.

^bOutcomes transformed using 100 × log_e so that regression coefficient represents percent change in outcome for each unit increase in age at puberty.