Fig. 4.
Blockade of GABAA receptors with bicuculline attenuates IML oscillations. (A) Extracellular oscillations are present in control conditions but are reduced by 10 μM bicuculline. (B) Power spectra of extracellular activity. A large 10 Hz peak is present in control conditions, but is reduced after treatment with bicuculline. (C) Autocorrelograms of the same segment of data analysed in (B). The activity is less strongly correlated following treatment with bicuculline. (D) Surface plot of oscillation power over time showing the time course of inhibition of oscillations by bicuculline and the subsequent recovery upon removal of the drug.